Package: caffsim 0.2.4.9000

Sungpil Han

caffsim: Simulation of Plasma Caffeine Concentrations by Using Population Pharmacokinetic Model

Simulate plasma caffeine concentrations using population pharmacokinetic model described in Lee, Kim, Perera, McLachlan and Bae (2015) <doi:10.1007/s00431-015-2581-x> and the package was published <doi:10.12793/tcp.2017.25.3.141>.

Authors:Sungpil Han [aut, cre]

# Install 'caffsim' in R:

install.packages('caffsim', repos = c('https://asancpt.r-universe.dev', 'https://cloud.r-project.org'))

Datasets:

On CRAN:

Last updated from:eb86245942. Checks:7 NOTE, 2 OK. Indexed: yes.

Target	Result	Time
linux-devel-x86_64	NOTE	179
source / vignettes	OK	191
linux-release-x86_64	NOTE	196
macos-release-arm64	NOTE	180
macos-oldrel-arm64	NOTE	238
windows-devel	NOTE	143
windows-release	NOTE	112
windows-oldrel	NOTE	111
wasm-release	OK	139

Help page	Topics
Create a concentration-time dataset of single oral dosing of caffeine	caffConcTime
Create a concentration-time dataset of multiple oral dosing of caffeine	caffConcTimeMulti
Calculate descriptive statistics of simulated pharmacokinetic parameters	caffDescstat
Calculate a duration of toxic concentration over specified levels (40 mg/L or 80 mg/L)	caffOverdose
Create a dataset of pharmacokinetic parameters of single oral dosing of caffeine	caffPkparam
Create a dataset of pharmacokinetic parameters of multiple oral dosing of caffeine	caffPkparamMulti
Plot plasma concentration-time curves of single oral dosing of caffeine	caffPlot
Plot plasma concentration-time curves of multiple oral dosing of caffeine	caffPlotMulti
Run Shiny app to interactively simulate single and multiple dosing for plasma caffeine concentration	caffShiny
Unit data of PK parameters	UnitTable